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While neural circuits involved in food-seeking behavior and satiety are known, Zhenggang Zhu, PhD, a postdoctoral researcher at UCSD, and colleagues investigated how the ventral tegmental area (VTA) dopamine neurons regulate the consumption of pleasurable foods using cell specific circuit mapping, optogenetics, and in vivo imaging

Because estrogen stimulates the endogenous synthesis of phosphatidylcholine via the phosphatidylethanolamine N-methyltransferase (PEMT) pathway, premenopausal women may be less likely to develop signs of choline deficiency in response to a low-choline diet compared to postmenopausal women (18, 19)