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While GLP-1, and to a slightly lesser degree exendin-4, form very stable interactions with R190 2.60 , Y152 1.47 , Y241 3.41 and E364 6.53 , exendin-P5, and in particular, oxyntomodulin, form much more transient interactions with these key residues
Maximum Absorption: Administered through intravenous (i.v.) or infusion, ensuring the best absorption and effectiveness
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Its principal physiological roles are regulation of postprandial glucose excursions and control of energy intake: amylin slows gastric emptying, inhibits post-prandial glucagon secretion and acts on hindbrain/hypothalamic centres to promote satiety, thereby complementing insulin in maintaining glucose homeostasis
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