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After gallbladder removal (cholecystectomy), bile flows continuously from the liver into the intestine rather than being stored, which can temporarily reduce fat digestion efficiency

Once cells were proliferating, they were moved up to higher cell volumes and adapted to DMEM cell culture media with 20% dFBS, 50 U ml 1 penicillin and streptomycin and 1 mM sodium pyruvate for at least 1 week before experimental setup

At week 52 in PIONEER 10, the use of additional anti-diabetic use and rescue medication use was 6% to 18% and 2% to 17%, respectively, for patients in semaglutide treatment groups and 12% and 9%, respectively in the dulaglutide treatment group

The parenteral segment dominated the market while holding the largest share of 88% in 2025 because injectable formulations provide precise dosing, rapid absorption, and sustained therapeutic effects, which are critical for achieving effective weight loss and glycemic control