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Venditti et al
The study found lower direct healthcare costs (inpatient care, outpatient care, and drug costs together) for empagliflozin initiators, with the differences in total costs between empagliflozin and GLP-1RA users mainly attributed to the higher drug price of GLP-1RA [24]
While GLP-1 primarily mediates glucose-dependent insulin secretion and appetite suppression, GIP influences insulin secretion and, based on preclinical studies, may affect lipid metabolism and other metabolic pathways
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