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That's not the goal
Li (Medpace Bioanalytical Labs) for assistance with in vivo pharmacokinetic studies
However, if NADH is not reoxidized here, it is used in reducing pyruvate to lactate by lactate dehydrogenase in the last step of the glycolysis
Simultaneously, insulin resistance, up- and downregulation of vessel GLUT and increased BBB permeability drive systemic hyperglycemia and reduced utilization of glucose at the cellular level [38, 58, 61]
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