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Research reference: safety & tolerability observations In controlled research environments, IGF-1 LR3 has generally been described as well-tolerated
However, the sample size in that study was small, as only 16 rats (eight per group) were used in their experiment, and the study duration was short (11 days), which may have affected the statistical significance and generalizability of the results
This problem can also be explained by intracellular glutathione deficiency because this tripeptide is critical for maintaining red blood cell membrane fluidity (17
Lancet 359 , 21882194 (2002)
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