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[1] [7] Bundling them is a mechanistic contrast, not a claim that they are equivalent or interchangeable
However, significant structural changeslasting onesresult from consistent use over 3 months or more, as this is the time it takes for collagen to rebuild effectively
Most considerations of non-animal alternatives for skin irritation/sensitization testing tend to examine a single aspect of the process (e.g., chemical reactivity, epidermal bioavailability, dendritic cell responses)
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