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Dose adjustments may be necessary based on individual tolerance and clinical response patterns
Science 331 , 16211624 (2011)
Oral mucosal melanin hyperpigmentation may be secondary to disease, medications, or smoking, and physiological oral melanin hyperpigmentation may be clinically and histopathologically similar so that the differentiation between pathological and physiological oral melanosis can at times be difficult
This mechanism aids in better glycemic control and can also contribute to weight loss
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