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Both are growth hormonereleasing peptides, but tesamorelin is FDA-approved for reducing visceral fat in HIV-related lipodystrophy, while ipamorelin is more commonly used in wellness and performance settings.

Individuals with a sensitivity to this type of cosmetic procedure can receive a topical anesthetic or over-the-counter pain medication to alleviate any discomfort they experience without influencing the results of the procedure

In June 2023, Lilly reported that Orforglipron led to an average weight loss of up to 14.7% over 36 weeks in adults with obesity or overweight based on Phase II trial results