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Research has demonstrated that Dihexa binds to HGF with remarkably high affinity (Kd = 65 picomolar) and acts as an allosteric modulator, potentiating HGF activity even at subthreshold concentrations

The present findings are supported by the results of the SECRET trial, which showed that non-pharmacologic body weight reduction achieved through caloric restriction improved exercise capacity in patients with the obesity phenotype of HFpEF 15

However, a healthcare provider may adjust this schedule depending on your response, including whether you get any side effects