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Unlike somatic cells, which possess a variety of DNA repair pathways to correct oxidative damage, spermatozoa have only one active DNA repair enzyme, 8-oxoguanine DNA glycosylase (OGG1), which is responsible for repairing oxidative base lesions ( 3.3 Protein oxidation Protein oxidation represents another key mechanism by which oxidative stress impairs sperm function
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The main safety concern is the unknown effect on melanocytes (pigment-producing cells), particularly in people with a history of melanoma or atypical moles
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