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Integrative multi-omics platforms are decoding the global architecture of stress responses with unprecedented resolution, while precision genome editing enables targeted manipulation of master regulators

Hair follicles are sensitive to oxidative damage, which can disturb and hamper their growth cycle and lead to thinning or hair loss

High levels of GSH support an anti-inflammatory M2 macrophage phenotype, which is essential for tissue repair and resolving inflammation

TUDCA reduces ER stress and neurodegeneration in HD, PD, and ALS models, 418 while 4-PBA improves motor function and reduces ER stress in AD, PD, and HD models