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It is used in conjunction with a reduced-calorie diet and increased physical activity to maximize its effectiveness
99% purity is essential for all melanocortin receptor pharmacology studies, comparative SAR research, pro-sexual behaviour paradigms, and melanogenesis biology , where impurities including the linear uncyclised peptide, partially oxidised species, or C-terminal amide hydrolysis product (PT-141) would show altered receptor subtype selectivity and confound mechanistic attribution
doi: 10.1016/j.psychsport.2014.03.007 43 AlsaeedIAlabkalJR
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