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Having a metabolic disease such as obesity or type 2 diabetes, as well as a low-choline, methionine, or inositol diet, can make weight loss difficult
The Evidence: "GLP-1 peptide is 100% homologous between cats and humans, making incretin-based therapies physiologically viable for feline patients." This homology is crucial
The peptides occupy the extracellular domain and the orthosteric pocket, whereas the small molecules wedge into the transmembrane region around Trp33
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