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Patients should expect some fluctuations in their symptoms during this time, but with proper treatment, these should subside over time
Research suggests that food noise may be linked to dysregulation in appetite-controlling hormones and neural pathways
Regular specialist review (at least annually) is mandatory to reassess whether valproate remains the most appropriate therapy, with completion of a Risk Acknowledgement Form to document patient understanding
The ensuing phagocytosis of RBCs may lead to iron overload within macrophages, which has been shown to cause progressive macrophage dysfunction, inflammatory M1 polarization, increased ferroptosis and exacerbated atherosclerosis 66,67,68,69,70,71
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