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doi: 10.1016/j.diabet.2023.101470 27 PelleMCZaffinaIGiofreFPujiaRArturiF

33 Isabel Tristn analyzed 80 serum and urine samples from COVID-19 patients (34 in intensive care and 46 hospitalized) and 32 healthy controls, identifying various metabolites, including TMAO, that could serve as biomarkers for the diagnosis, prognosis and severity assessment of COVID-19

Flare-ups often coincide with the consumption of histamine-laden foods or environmental allergens

Firstly, activated NF-B and NLRP3 inflammasome in DN promotes inflammation and increases fibronectin and collagen deposition in kidney, 41,42 leading to thickening glomerular basement membrane, glomerular sclerosis, podocyte damage, and ultimately kidney fibrosis