In three nested casecontrol studies from England and Wales, involving 440,089 patients with T2DM and without ASCVD treated with non-insulin glucose-lowering medication, combined SGLT2i and GLP-1RA therapy used for primary prevention was associated with 30% lower odds of MACE (defined as myocardial infarction/acute coronary syndrome, stroke/transient ischemic attack, and/or cardiovascular death) compared with other combination regimens (OR, 0.70
Obstetrics and Gynecology Clinics of North America, 29 (11), 768780
Multivitamins do not include therapeutic doses of fiber, probiotics, creatine, HMB, or omega-3s
These drugs alter insulin signaling, digestion, and appetite suppression by slowing gastric emptying and changing how quickly food moves through the gastrointestinal tract