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Huo Y, Li J, Qin X, et al
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Following dietary guidance helps you get the most from your treatment
However, patients with HCC often develop resistance to TKIs and this resistance development is associated with increased IGFBP-1 expression, the aggregation mechanism manifested by TKI-induced hypoxia increasing IGFBP-1 expression through activation of HIF-1 and HIF-2
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