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[1] [2] Hormone replacement therapy (HRT) encompasses various formulations of estrogen, progesterone, or combination therapies used primarily to manage menopausal symptoms such as hot flashes, night sweats, and vaginal dryness
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Alternatives might include switching to a different GLP-1 medication (some patients tolerate one better than another despite similar mechanisms), reducing the maintenance dose to a level that produces fewer GI effects while still providing benefit, or transitioning to tirzepatide or another agent in the class
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