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The evidence SURMOUNT-1 randomised adults with obesity or overweight to weekly tirzepatide or placebo for 72 weeks
Host microbiota constantly control maturation and function of microglia in the CNS
That dual mechanism produces powerful metabolic effects, but it also amplifies gastrointestinal side effects in some individuals
For eligible patients, Lilly also offers single-dose vials, starting at $299, $399, and $449 per month, depending on dose, when refills are completed within 45 days
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