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This program was established to test how a category of drugs for weight management becoming available under Medicare might impact beneficiaries and the Medicare program
We extracted data on the following variables: study characteristics (author, year, country, study design, sample size, demographic characteristics of study participants, inclusion and exclusion criteria), intervention types, outcome measures, and duration of treatment (weeks)
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Higher mean age and baseline SBP, greater use of anti-hypertensive medications, longer T2D duration, and reduction in insulin daily dose might have contributed to explain the difference observed in the impact of weight loss on SBP reduction in these trials, although direct GLP-1R- and GIP-R-mediated effects could also be considered [77]
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