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Semaglutide is an injectable prescription medication for adults who are either overweight, obese, or otherwise struggle with chronic weight management
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Adult patients with T2DM treated by metformin, thiazolidinediones/rosiglitazone or both without adequate glycaemic control after 3 months were enrolled in SUSTAIN 2 trial to explore the comparative effectiveness of semaglutide against sitagliptin
Originally developed for the treatment of type 2 diabetes mellitus, these agentsincluding semaglutide and tirzepatidehave demonstrated substantial efficacy in promoting weight loss and are increasingly reshaping therapeutic strategies for obesity, cardiovascular and kidney disease, and potentially substance use disorders.[1,2] Historically, paradigm-shifting therapeutics have periodically redefined clinical practice
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