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The evidence is unclear or shows little to no benefit from using B12 supplementation, but more research is needed in these areas

In muscle injury model studies, muscle injury (such as trauma, exerciseinduced injury, or diseaserelated damage) triggers a series of pathophysiological processes including myofiber rupture, inflammatory responses, and muscle stem cell activation

These injections are particularly helpful for individuals who have difficulty absorbing B12, as well as those who have undergone gastric surgery, since they make it possible for B12 to be absorbed without first being digested

[121] Age is also a contributing factor: elderly individuals are often achlorhydric due to reduced parietal cell function in the stomach, increasing their risk of vitamin B 12 deficiency