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Typically, it's prescribed for adults with a body mass index (BMI) of 30 kg/m or greater, or a BMI of 27 kg/m or greater with at least one weight-related condition (like high blood pressure, type 2 diabetes, or high cholesterol)
Given existing evidence, triple combination therapy can be expected to provide additional cardiorenal protection, although further randomized controlled trials are needed to determine whether triple combination therapy actually has additive or synergetic effects compared with mono or dual therapy
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GLP- 1 Receptor Agonists in Combination with Insulin The GLP- 1 receptor agonists have been shown to improve blood glucose control when used in conjunction with insulin, particularly basal insulin, and may be particularly useful in the treatment of advanced T2DM [108]
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