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This is one reason MOTS-c is frequently discussed in longevity, performance, and metabolic-health communities
Systemic bioavailability with standard oral forms is very low Oral vs
In a systematic review, poor glucose regulation is associated with diminished lung function, worsened asthma severity, and increased hospitalizations [45, 46]
The only published human data is a small IRB-approved safety pilot (2 people, intravenous dosing) that found no adverse effects, which is not enough to establish safety for the general population or for self-administered subcutaneous use
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