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The formal clinical literature defines this threshold as intestinal failure: a reduction of gut function below the minimum necessary for absorption of macronutrients, water, and electrolytes, such that IV supplementation is required to maintain health
Human ovarian adenocarcinoma cells SKOV-3 (ATCC HTB-77) were from American Type Culture Collection (ATCC, Manassas, VA, USA)
The drug had previously been approved by the FDA in 2014
Older adults and those with coronary disease typically require lower doses
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