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Oxidative stress arises from an imbalance between the production of free radicals and the ability to neutralize them with antioxidants like glutathione, which can lead to serious cellular damage
Treatment of hyperlipemic mice with the ferroptosis inhibitor ferrostatin-1 (Fer-1) significantly decreases the development of atherosclerosis in ApoE-/- mice fed HFD for 1216 weeks 79
The leucine is cleaved first, the serine second, and the glycine third, as demonstrated by the sequential analysis
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