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Some people may prefer a pill over an injectable, and most importantly, oral medications are more cost-effective to create, so they are less expensive and more accessible. The pills are slightly less effective than injectable semaglutide: Studies found that people who took 25 or 50 mg doses of oral semaglutide for 14 months lost about 13% of their body weight

The identification of a distinct, non-IGF-1R MGF receptor remains an active research goal