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Methylfolate is the only metabolite of folate that can cross the blood-brain barrier, and plays a key role in cell metabolism, protein methylation, and the synthesis of the monoamine neurotransmitters

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The peptide sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) is entirely stable in an aqueous solution, a property that distinguishes it from many other peptides that degrade rapidly in the gut or bloodstream

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