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Popular GLP-1 Receptor Agonists Some of the well-known GLP-1 receptor agonists include: There are four GLP-1 agonist medicines approved by the Therapeutic Goods Administration (TGA) for use in Australia for the management of Type 2 Diabetes: dulaglutide (Trulicity) semaglutide (Ozempic) tirzepatide (Mounjaro) liraglutide (Saxenda)
Even where list and net prices are much lower, reimbursement authorities are treading cautiously
The most important serious side effects include acute pancreatitis (severe persistent abdominal pain radiating to the back, though clinical trials found similar pancreatitis rates to comparators), severe dehydration from persistent vomiting or diarrhea (signs include dizziness, decreased urination, extreme thirst), gallbladder disease including cholecystitis or cholelithiasis (right upper quadrant pain, fever, jaundice), severe allergic reactions (difficulty breathing, swelling of face or throat), and severe hypoglycemia when combined with insulin or sulfonylureas (confusion, loss of consciousness, seizures)
I do fully understand, though, that there will be situations in which using them makes some sense
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