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Your brain genuinely registers less hunger
Clinical Trial Data: The Numbers Semaglutide: STEP 1 Trial The STEP 1 trial enrolled 1,961 adults with obesity or overweight
Antidepressant medication use, weight gain, and risk of type 2 diabetes
When the pharmacological appetite suppression is reduced or withdrawn, the caloric threshold required to maintain their new weight is lower than expected, but their appetite, shaped by the neurological reward pathways that GLP-1s modulate, does not stay suppressed indefinitely without ongoing treatment
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