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The 2001 ternary-complex JBC paper, the 2004 Nature cardiac-repair paper, the 2002 corneal alkali-injury paper, and the 1997 FASEB endothelial-migration paper collectively form the foundational stack (PMID 11579089, PMID 15565145, PMID 11950239, PMID 9194528)
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Originally developed for the management of type 2 diabetes, semaglutide has shown additional benefits beyond glycemic control
While these symptoms have many potential causes, they require evaluation to rule out thyroid pathology, given the FDA's boxed warning regarding thyroid C-cell tumors
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