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Serum icodec concentrations were measured following IcoSema and icodec administration using a validated luminescence oxygen channelling immunoassay (LOCI)

The cited evidence includes the patent's listing in the FDA Orange Book, August 2024 investor-call statements by Hims's CEO acknowledging that semaglutide was not going off patent, and a formal demand letter Novo sent on February 8, 2026, one day before filing