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J Surg Orthop Adv
At the level of cytokine/chemokine profiles and tolerance-inflammation balance, efficiently cleared apoptotic cells tend to induce anti-inflammatory factors such as TGF- and IL-10, promoting immune tolerance and tissue repair (140)
Despite the absence of adverse cardiovascular effects has been confirmed, this benefit was not verified in an integrated analysis of 12 controlled, randomized, short-term clinical trials (12-52 weeks) comparing exenatide with placebo or insulin [72]
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