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The molecule has to penetrate the stratum corneum (the skin's outer barrier) to reach the dermis where collagen is actually produced
When compared with the respective CON-fed groups, EtOH dramatically induced hepatic protein carbonylation in both WT and KO mice, albeit the levels in the KO mice remained higher than those observed in WT mice
Journal of Molecular Medicine (2017) 3
This conversion requires the enzyme glutamatecysteine ligase (GCL, glutamate-cysteine synthase)
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