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2025 Jan 24;11(4):eadp4765
ROS Overproduction: The Initiating Driver Hyperglycaemia activates multiple simultaneous ROS sources, including mitochondrial uncoupling, NADPH oxidase isoforms NOX2 and NOX4, and xanthine oxidase upregulation
Meanwhile, PA decreased the levels of GLUT4 and phosphorylation of Akt and affected SESN2 expression
The formulation is synergistically enhanced by Vitamin C (Ascorbic Acid), which is crucial for collagen synthesis (essential for skin structure) and significantly boosts the effectiveness and regeneration of Glutathione
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