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80 Phlorizin, the first SGLT-2i, is a naturally occurring chalcone compound discovered in apple bark in the 1850s by French researchers
However, larger, prospective trials are now needed to fully evaluate their safety and efficacy in type 1 diabetes patients living with overweight and obesity. Reference: Semaglutide and tirzepatide lead to better blood sugar control and weight loss in individuals with type 1 diabetes, US study finds, Diabetologia, Meeting: Annual Meeting of the European Association for the Study of Diabetes (EASD)
Safety precautions If you plan to use compounded GLP-1 medications like compounded semaglutide, purchase the medication from a licensed and reputable compounding pharmacy or FDA-registered outsourcing facility to make sure you receive legitimate products
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