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Data extraction Information on baseline characteristics and outcomes was extracted, including age, gender, proportion of patients with type 2 diabetes (T2D), baseline BMI, percentage total body weight loss (TBWL%), waist circumference, body composition, proportion of patients achieving at least 5%, 10%, 15%, 20% and 25% body weight reduction, remission or improvement/resolution of obesity-related complications, serious adverse events (SAE), mortality, major adverse cardiovascular events (MACE), fasting plasma glucose (FPG), HbA1c, lipid profile, estimated glomerular filtration rate (eGFR), creatinine, albuminuria, mental health parameters and quality of life (QoL)