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Safety, Tolerability, and Who Should Consider Each Option Both semaglutide and tirzepatide carry similar GI side effects (nausea, vomiting, diarrhea, constipation), with tirzepatide potentially causing slightly more nausea in early weeks due to its dual mechanism
In this post, I take a deep dive into EVOKE and EVOKE+, examining trial design, endpoints, effect sizes, and interpretability
Magnesium plays a role in muscle recovery
Resources Li, Xiangyu, et al
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