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It may also be beneficial to consider individuals at high risk for prodromal PD
Most patients have none beyond mild tingling, slight redness, or a little dryness in the first week, and that usually settles as your skin adjusts
What that does not establish is any quantitative claim about how much the fasted-versus-fed difference matters for this blend at any modeled amount only that the direction of the effect is real and the timing logic is not arbitrary
Tan et al., 1999)
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