Moreover, excessive reactive oxygen species (ROS) and inflammatory cytokines secreted from macrophages and other immune cells [e.g., interferon- (IFN) and tumor necrosis factor (TNF)] can arrest the anagen phase, driving premature telogen and catagen phases, inducing apoptosis in the follicular microenvironment, leading to miniaturization and reduced hair density [2, 4, 5]
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The pathological association between nutrition and OA Obesity and OA: intertwined pathways of inflammation, mechanics, and diet Obesity is a critical risk factor for OA, driven by a synergy of mechanical overload and adipose tissue-mediated systemic inflammation
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