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He was surprised that although the [very low-calorie diet] resulted in greater reductions in weight, fat mass, and insulin resistance, it did not appear to enhance beta cell function. The authors suggest that this is because the participants had been living with type 2 diabetes for a long time
PubMed Geerling BJ, Dagnelie PC, Badart-Smook A, et al
Some people tolerate one better than the other, which matters when adding illness to the equation
In the brain, neurons involved in appetite control have devoted GLP-1 receptors
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