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While extremely high doses of vitamin B12 can lead to toxicity, excess amounts are excreted in the urine
Common side effects include injection site reactions (burning, pain, swelling, redness), headache, mild diarrhea, and upset stomach
Chiu S, Mulligan K, Schwarz J-M
To optimize absorption and minimize local irritation, it is recommended to rotate injection sites, such as the upper arms, thighs, and areas around the navel
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