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Menopause can also be induced by therapies that are toxic to the ovaries, such as radiation therapy and some chemotherapies, or by treatment with anti-estrogenic drugs, such as those used to treat endometriosis or breast cancer

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MOTS-c intervention Rats in the DM and DME groups were injected intraperitoneally with MOTS-c (0.5 mg/kg/day, 7 days/week, GL Biochem Shanghai Ltd

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