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Iron overload cardiomyopathy Pathological and physiological conditions such as thalassemia and sickle cell disease, chronic liver disease, Friedreich ataxia, delayed skin porphyria, excessive dietary iron intake, and other rare diseases that lead to abnormal iron metabolism, such as congenital transferrin deficiency, in addition to recurrent transfusion, ineffective haematopoiesis, peripheral haemolysis, and increased gastrointestinal iron absorption, are reasons for iron overload in primary and secondary haemochromatosis patients (including , )

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