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In a 68- and 72-week clinical trial studying Wegovy (2.4 mg) and Zepbound (15 mg) in patients without diabetes and with BMI 30, or BMI 27 with a weight-related condition, the average weight loss was 15% and 20%, when paired with diet and exercise changes (compared to 2.4% and 3.1%, respectively, with diet and exercise alone)

It already outperformed semaglutide head-to-head, and for many people who plateaued on a GLP-1-only drug, switching to tirzepatides dual mechanism is exactly the change that restarts progress

Nat Commun 8 , 14835 (2017)

At this point, your dose will be reviewed and your blood sugar levels checked by a doctor