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Reduced calorie diet combined with NNMT inhibition establishes a metabolic memory
Subcutaneous B12 administration, although promising in select cases such as congenital cobalamin disorders, lacks comprehensive comparative studies against IM and oral routes
Phase 2 trials (Jastreboff et al., NEJM, 2023) have shown it to be highly effective for weight reduction in adults with obesity
If you are deficient in B12, a course of injections or high dose oral supplementation may be advised
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