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For IC 50 calculations with dengue virus, phenformin or atpenin A5 were prediluted in Huh7.5 complete media and added to Huh7.5 cells 1 h before adding the virus (MOI = 1)

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Can-Fite BioPharma completed enrollment of the first 247 patients, triggering the pre-specified interim analysis of its pivotal Phase 3 trial (NCT06643260) for piclidenoson, a first-in-class oral A3 adenosine receptor (A3AR) agonist, in moderate-to-severe plaque psoriasis