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Direct GLP-1-mediated suppression of joint inflammation has been suggested by preclinical models but not demonstrated in human RA patients taking tirzepatide
Most patients can safely continue their medication with appropriate eye monitoring and treatment
Latifian et al
The MHRA and EMA continue to monitor rare reports of non-arteritic anterior ischaemic optic neuropathy (NAION) in semaglutide users, though causality is unestablished
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