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Body surface area scaling, which is commonly used to extrapolate rodent doses to larger species, has known limitations for peptides specifically, because peptides are subject to enzymatic degradation in ways that small molecules aren't
Chakrabarti, P
D.VivarelliF.CanistroD.PaoliniM.et al (2019)
NSL literature pointer PMID 8258269 L-Carnitine laboratory index [PMID: 8258269] National Science Labs indexing note for PMID 8258269: review the PubMed methods, models, and limitations before citing
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